LFS works like a charm under plain Wine for me. Using Ubuntu dapper 6.06 i386 I selected Wine in synaptic and it worked right away. I have no existing Windows installation on that drive: Wine is not piggybacking on an already working installation.
Cons:
no shadows (no big deal)
dials mess up on dash if I use shift-f4
problems getting to full-screen with LFS on top
joystick range and/or deadzone
no force-feedback
Now the last 2 are what make me have windows installed still. I realise that the deadzone and joystick range problems are due to Wine's joystick mapper because in Ubuntu my joystick range is fully detected. So I am needing basically the logitech profiler in Wine.
For the force-feedback, I think it should work, I'm just too lazy to compile the code I found that sends the force messages to the controller. Certainly LFS is already generating these messages
Performance is 80fps+ running on Athlon 64 2Ghz + geforce 7600GT.
hth