I had a clean install of Vista, installed for maybe 3 weeks at the time I first tried the G25, had almost nothing installed on my system, no antivirus, just office 2003, some games, photoshop, dreamweaver and that is about it. Installed the drivers, rebooted and windows would no longer boot. was frustrating. At the time I went to logitech's forums and read other posts about similiar problems and that logitech was aware and was working on a new driver.