It's different for everyone. I used to drive with the virtual steering on, but without the driver for some time. I got used to it. Then, I put the driver on and had to get used to the driver's hand animation when I turned, because the default cockpit view on cars like FBM don't look quite right. The driver appears to be sitting too far back and almost stretching to reach the steering wheel.
I zoomed in a bit and it was better, but still not ideal, because the mirrors go beyond the screen if you zoom in to the point where you think you're sitting in the right place. I also raced without the virtual wheel and driver, and got used to that too. It all depends on what reference one uses. The early hiccups with, without the driver and virtual wheel, I think, have to do with counter intuitiveness about where you're sitting, driver animation, virtual wheel movements, etc. Ultimately, we all use the road and our relative position with the road as reference.
One big disadvantage with keyboard input for throttle, brakes is that you've got to mimic lifting and braking by intermittent dabs on the throttle and brakes, which will unsettle cars sometimes. It slows you down also. Light and steady input on pedals would, in theory, make cars more stable and fast. Keyboard input also has an advantage in that you don't get any penalty for depressing the pedals too quickly, too much. No such thing.
Mouse steering is better than keyboard, and again there are advantages and disadvantages to this compared to wheels. It's very tough to recover from a spin on faster cars, because you're using one hand and shaking it sideways on a table. On the bright side, mouse steering doesn't tire you physically. A good, wheel, however, makes life fun
. I have a wheel, which has input lag from the 50s, 180 degrees total rotation, and the brake and throttle pedals are just big depressible buttons. Once you touch it, it's either full throttle or full brakes. Waste of springs lol. The only car I've been able to drive and enjoy life as a result is the mini cooper from GT Legends.
Peace be upon those who don't have the G27!
But, at the end, if anyone can get past the difficulties with any given input device, life is going to be fun, no doubt!