Yes.
Examples:
Rudy van Buren
Norbi Kiss
Tommy Ostgaard
Scott Andrews
Wyatt Gooden
I dare say that's because they have "natural talent" rather than just by practising for days on end but yes they correlate pretty well. From the small amount of karting I've done I dare say I'm better IRL than I am online, but I may reconsider that after I've hopefully done some proper karting next year
EDIT: The skills are exactly the same, the only real difference is the physical side (which is the bit I tend to struggle with IRL :P)