Yeah, get a 45 nm CPU (E8200, E8400 if you can), forget the 'if i need more power i'll add another card' s**t since it's useless - by the time you'll need more power, it'll be hard to get a GFX that you have now, they will be too slow (SLI scales badly, really badly) and will use too much power. Having 2 HDs will be hard, if so, forget IDE optics - you'll have to buy SATA DVD drives. I'd loose the 80 gig HD since IDE is mostly slow on P35 - it's done via another chip and is not supported out fo the box via the chipset.
There's a new mobo out there, P5K PRO - very good value for money and Bit-Tech just put up a review of it. Seems it's a good performer and costs 80 pounds.